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1

Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity

Wei Yang, Jae Young Lee, Marcin Nowotny

Journal:

Year:

2006

Language:

english

File:

PDF, 380 KB

english, 2006

2

Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD

Nowotny, Marcin, Cerritelli, Susana M, Ghirlando, Rodolfo, Gaidamakov, Sergei A, Crouch, Robert J, Yang, Wei

Journal:

The EMBO Journal

Year:

2008

Language:

english

File:

PDF, 459 KB

english, 2008

3

Retroviral integrase superfamily: the structural perspective

Nowotny, Marcin

Journal:

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

4

Structure of UvrA nucleotide excision repair protein in complex with modified DNA

Jaciuk, Marcin, Nowak, Elżbieta, Skowronek, Krzysztof, Tańska, Anna, Nowotny, Marcin

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

5

Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release

Nowotny, Marcin, Yang, Wei

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 449 KB

english, 2006

6

Effects of K channel inhibitors on potassium transport in bovine adrenal chromaffin granules

Nikolai A. Lobanov, Adam Szewczyk, Grazyna Wójcik, Marcin Nowotny, Maciej J. Nałęcz

Journal:

Year:

1997

Language:

english

File:

PDF, 426 KB

english, 1997

7

Structural and functional modules in RNA interference

Marcin Nowotny, Wei Yang

Journal:

Current Opinion in Structural Biology

Year:

2009

Language:

english

File:

PDF, 2.77 MB

english, 2009

8

AP2-like cis element is required for calretinin gene promoter activity in cells of neuronal phenotype differentiated from multipotent human cell line DEV

Katarzyna Billing-Marczak, Leonora Buzanska, Lois Winsky, Marcin Nowotny, Tomasz Rudka, Krystyna Isaacs, Marie F. Belin, Jacek Kuznicki

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2002

Language:

english

File:

PDF, 421 KB

english, 2002

9

Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis

Marcin Nowotny, Sergei A. Gaidamakov, Robert J. Crouch, Wei Yang

Journal:

Year:

2005

Language:

english

File:

PDF, 1.59 MB

english, 2005

10

Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription

Marcin Nowotny, Sergei A. Gaidamakov, Rodolfo Ghirlando, Susana M. Cerritelli, Robert J. Crouch, Wei Yang

Journal:

Year:

2007

Language:

english

File:

PDF, 2.58 MB

english, 2007

11

Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription

Marcin Nowotny, Sergei A. Gaidamakov, Rodolfo Ghirlando, Susana M. Cerritelli, Robert J. Crouch, Wei Yang

Journal:

Year:

2007

Language:

english

File:

PDF, 35 KB

english, 2007

12

Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage

Monika P. Rychlik, Hyongi Chon, Susana M. Cerritelli, Paulina Klimek, Robert J. Crouch, Marcin Nowotny

Journal:

Year:

2010

Language:

english

File:

PDF, 2.06 MB

english, 2010

13

Catalytic Mechanism of RNA Backbone Cleavage by Ribonuclease H from Quantum Mechanics/Molecular Mechanics Simulations

Rosta, Edina, Nowotny, Marcin, Yang, Wei, Hummer, Gerhard

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 3.39 MB

english, 2011

14

Ty3 reverse transcriptase complexed with an RNA/DNA hybrid shows structural and functional asymmetry

Bona, Marion, Nowak, Elzbieta, Miller, Jennifer T, Ogendi, Brian, Nowotny, Marcin, Le Grice, Stuart FJ

Journal:

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

15

Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry

Nowak, Elżbieta, Miller, Jennifer T, Bona, Marion K, Studnicka, Justyna, Szczepanowski, Roman H, Jurkowski, Jakub, Le Grice, Stuart F J, Nowotny, Marcin

Journal:

Nature Structural and Molecular Biology

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

16

Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

Mathys, Hansruedi, Basquin, Jérôme, Ozgur, Sevim, Czarnocki-Cieciura, Mariusz, Bonneau, Fabien, Aartse, Aafke, Dziembowski, Andrzej, Nowotny, Marcin, Conti, Elena, Filipowicz, Witold

Journal:

Year:

2014

Language:

english

File:

PDF, 2.82 MB

english, 2014

17

Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease

Gaur, Vineet, Wyatt, Haley D.M., Komorowska, Weronika, Szczepanowski, Roman H., de Sanctis, Daniele, Gorecka, Karolina M., West, Stephen C., Nowotny, Marcin

Journal:

Year:

2015

Language:

english

File:

PDF, 3.41 MB

english, 2015

18

Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation

Smietanski, Miroslaw, Werner, Maria, Purta, Elzbieta, Kaminska, Katarzyna H., Stepinski, Janusz, Darzynkiewicz, Edward, Nowotny, Marcin, Bujnicki, Janusz M.

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.97 MB

english, 2014

19

Structure and mechanism of nucleases regulated by SLX4

Nowotny, Marcin, Gaur, Vineet

Journal:

Current Opinion in Structural Biology

Year:

2016

Language:

english

File:

PDF, 1.71 MB

english, 2016

20

Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli

Stracy, Mathew, Jaciuk, Marcin, Uphoff, Stephan, Kapanidis, Achillefs N., Nowotny, Marcin, Sherratt, David J., Zawadzki, Pawel

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

21

Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase

Figiel, Małgorzata, Krepl, Miroslav, Poznański, Jarosław, Gołąb, Agnieszka, Šponer, Jiří, Nowotny, Marcin

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 3.92 MB

english, 2017

22

The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain

Charbonnel, Cyril, Niazi, Adnan K., Elvira-Matelot, Emilie, Nowak, Elżbieta, Zytnicki, Matthias, de Bures, Anne, Jobet, Edouard, Opsomer, Alisson, Shamandi, Nahid, Nowotny, Marcin, Carapito, Christine

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 4.01 MB

english, 2017

23

Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase

Figiel, Małgorzata, Krepl, Miroslav, Park, Sangwoo, Poznański, Jarosław, Skowronek, Krzysztof, Gołąb, Agnieszka, Ha, Taekjip, Šponer, Jiři, Nowotny, Marcin

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 5.40 MB

english, 2017

24

5′-Phosphorothiolate dinucleotide cap analogs: reagents for mRNA modification and potent small molecular inhibitors of decapping enzymes

Wojtczak, Blazej Andrzej, Sikorski, Pawel J., Fac-Dabrowska, Kaja, Nowicka, Anna, Warminski, Marcin, Kubacka, Dorota, Nowak, Elzbieta, Nowotny, Marcin, Kowalska, Joanna, Jemielity, Jacek

Journal:

Journal of the American Chemical Society

Year:

2018

Language:

english

File:

PDF, 3.69 MB

english, 2018

25

Crosslink and shield: protecting abasic sites from error-prone repair

Nowotny, Marcin

Journal:

Nature Structural and Molecular Biology

Year:

2019

Language:

english

File:

PDF, 908 KB

english, 2019

26

RNases H: Structure and mechanism

Hyjek, Malwina, Figiel, Małgorzata, Nowotny, Marcin

Journal:

Year:

2019

Language:

english

File:

PDF, 1.20 MB

english, 2019

27

RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution

Górecka, Karolina Maria, Krepl, Miroslav, Szlachcic, Aleksandra, Poznański, Jarosław, Šponer, Jiří, Nowotny, Marcin

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.68 MB

english, 2019

28

RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution

Górecka, Karolina Maria, Krepl, Miroslav, Szlachcic, Aleksandra, Poznański, Jarosław, Šponer, Jiří, Nowotny, Marcin

Journal:

Nature Communications

Year:

2019

File:

PDF, 1.68 MB

2019

29

Recognition and processing of branched DNA substrates by Slx1–Slx4 nuclease

Gaur, Vineet, Ziajko, Weronika, Nirwal, Shivlee, Szlachcic, Aleksandra, Gapińska, Marta, Nowotny, Marcin

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 2.27 MB

english, 2019

30

A combined structural and biochemical approach reveals translocation and stalling of UvrB on the DNA lesion as a mechanism of damage verification in bacterial nucleotide excision repair

Jaciuk, Marcin, Swuec, Paolo, Gaur, Vineet, Kasprzak, Joanna M., Renault, Ludovic, Dobrychłop, Mateusz, Nirwal, Shivlee, Bujnicki, Janusz M., Costa, Alessandro, Nowotny, Marcin

Journal:

Year:

2020

Language:

english

File:

PDF, 2.01 MB

english, 2020

31

Evolutionary history and activity of RNase H1-like proteins in Arabidopsis thaliana

KuciÅski, Jan, Chamera, Sebastian, Kmera, Aleksandra, Rowley, M Jordan, Fujii, Sho, Khurana, Pragya, Nowotny, Marcin, Wierzbicki1, Andrzej T

Journal:

Plant and Cell Physiology

Year:

2020

Language:

english

File:

PDF, 44.40 MB

english, 2020

32

Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins

Hyjek-SkÅadanowska, Malwina, Vickers, Timothy, NapiÃ³rkowska, Agnieszka, Anderson, Brooke, Tanowitz, Michael, Crooke, Stanley T., Liang, Xue-hai, Seth, Punit P, Nowotny, Marcin

Journal:

Journal of the American Chemical Society

Year:

2020

Language:

english

File:

PDF, 1.51 MB

english, 2020

33

Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA

Szewczyk, Maciej, Malik, Deepshikha, Borowski, Lukasz S, Czarnomska, SylwiaÂ D, Kotrys, Anna V, Klosowska-Kosicka, Kamila, Nowotny, Marcin, Szczesny, Roman J

Journal:

Nucleic Acids Research

Year:

2020

File:

PDF, 5.91 MB

2020

34

Disulfide bridge cross-linking between protein and the RNA backbone as a tool to study RNase H1

Hyjek-SkÅadanowska, Malwina, StasiÅska, Anna R., NapiÃ³rkowska, Agnieszka, BartÅomiejczak, Aneta, Seth, Punit P., Chmielewski, Marcin K., Nowotny, Marcin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2020

File:

PDF, 2.02 MB

2020

35

Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine

Malik, Deepshikha, KobyÅecki, Kamil, Krawczyk, PaweÅ, PoznaÅski, JarosÅaw, Jakielaszek, Aleksandra, NapiÃ³rkowska, Agnieszka, Dziembowski, Andrzej, Tomecki, RafaÅ, Nowotny, Marcin

Journal:

Nucleic Acids Research

Year:

2020

File:

PDF, 5.41 MB

2020

36

The expression of Rpb10, a small subunit common to RNA polymerases, is modulated by the R3H domain-containing Rbs1 protein and the Upf1 helicase

CieÅla, MaÅgorzata, Turowski, Tomasz W, Nowotny, Marcin, Tollervey, David, Boguta, Magdalena

Journal:

Nucleic Acids Research

Year:

2020

File:

PDF, 7.27 MB

2020